Monday, 22. August 2022

TimeProgram item
08:30 – 09:30Registration and coffee, put up posters
09:30 – 09:45 Welcome
9:45 – 12:15 Session 1 – Structural Biology of Chromatin
Chair: Thomas Schalch
9:45 – 10:15Structure & mechanisms of class I histone deacetylase complexes
John Schwabe, University of Leicester
10:15 – 10:453D genome structures of single differentiating mouse ES cells reveal a unique reorganisation of chromatin in the formative state
Ernest Laue, University of Cambridge
10:45 – 11:15An acetylation-dependent feed-forward reaction enables long-range chromatin interactions
Daniel Panne, University of Leicester
11:15 – 11:45 Coffee and Tea
11:45 – 13:05Session 2 – 3D Genome Organization
Chair: Hiroshi Kimura
11:45 – 12:15Spatial multi-omics for understanding gene expression regulated by cell-cell interaction
Yasuyuki Ohkawa, Kyushu University
12:15 – 12:45Chromatin behavior in living cells revealed by single-nucleosome imaging/tacking
Kazuhiro Maeshima, National Institute of Genetics
12:45 – 13:5Visualising chromatin dynamics in living cells at the domain level
Andrew Bowman, University of Warwick
13:05 – 13:30Lunch
13:30 – 14:30Poster session
14:30 – 16:20 Session 3 – Chromatin in Development
Chair: Shaun Cowley
14:30 – 15:0A critical role for H3K9 methylation in mitotic chromosome bookmarking and compaction
Mandy Fisher, Imperial College London
15:0 – 15:30Quantification of sperm chromatin condensation
Yuki Okada, University of Tokyo
15:30 – 16:0Canonical PRC1 Is Recruited To Target Genes By JARID2-PRC2 Independently of H3K27me3
Adrian Bracken, Trinity College Dublin
16:0 – 16:20JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation
Manuel Tavares, UCL Cancer Institute
16:20 – 16:50Coffee and Tea
16:50 – 18:00Session 4 – Chromatin and RNA
Chair: Jun-ichi Nakayama
16:50 – 17:20Understanding and reconstructing small RNA-mediated heterochromatin formation
Yuka Iwasaki, Keio University
17:50 – 18:10Investigating the effects of LINE1 promoters’ activity in colon cancer
Cristina Tufarelli, University of Leicester
19:30 pmConference Dinner at College Court

Tuesday, 23. August 2022

9:30 – 09:00Coffe and Tea
9:00 – 10:50Session 5 – Gene Regulation
Chair: Yuki Okada
9:0 – 9:30Unlocking the differential activities of HDAC1/2 complexes: How many machines does it take to build a road..?
Shaun Cowley, University of Leicester
9:30 – 10:0Control of signal-responsive enhancer resetting by chromatin remodelling proteins
Brian Hendrich, University of Cambridge
10:0 – 10:30Understanding how CpG islands regulate gene expression
Rob Klose, University of Oxford
10:30 – 10:50Investigating the roles of BET bromodomain proteins in DNA replication and repair
Eva Petermann, University of Birmingham
10:50 – 11:20Coffee and Tea
11:20 – 13:00Session 6 – 3D Genome Organization
Chair: Yuka Iwasaki
11:20 – 11:50Dynamics of Histone and RNA Polymerase II Modifications in Living Cells
Hiroshi Kimura, Tokyo Institute of Technology
11:50 – 12:20Replication dynamics identifies the folding principles of the inactive X chromosome
Ichiro Hiratani, RIKEN
12:20 – 12:40Cohesin-independent STAG proteins interact with RNA and localise to R-loops to promote complex loading
Yang Li, University College London, Cancer Institute
12:40 – 13:15Lunch
13:15 – 14:00Poster session
14:00 – 15:30Session 7 – Heterochromatin
Chair: Daniel Panne
14:0 – 14:30Epigenetic Regulation, Heterochormatin and Antifungal Resistance
Robin Allshire, University of Edinburgh
14:30 – 15:0Mechanisms regulating Clr4/SUV39H histone methyltransferase activity
Junichi Nakayama, National Institute for Basic Biology
15:0 – 15:30Histone ubiquitination marks antagonize to compartmentalize the genome
Thomas Schalch, University of Leicester
15:30 – 16:00Coffee and Tea
16:00 – 17:20Session 9 – Chromatin remodelling
Chair: John Schwabe
16:0 – 16:20Proteomic profiling reveals distinct phases to the restoration of chromatin following DNA replication
Constance Alabert, University of Dundee
16:20 – 16:50Epigenetic changes arising from acute depletion of the tumour suppressor ARID1A.
Tom Owen-Hughes, University of Dundee
16:50 – 17:00Closing Remarks and Departure