Monday, 22. August 2022
| Time | Program item |
|---|---|
| 08:30 – 09:30 | Registration and coffee, put up posters |
| 09:30 – 09:45 | Welcome |
| 9:45 – 12:15 | Session 1 – Structural
Biology of Chromatin Chair: Thomas Schalch |
| 9:45 – 10:15 | Structure & mechanisms of class I histone deacetylase complexes John Schwabe, University of Leicester |
| 10:15 – 10:45 | 3D genome structures of single differentiating mouse ES cells reveal a unique reorganisation of chromatin in the formative state Ernest Laue, University of Cambridge |
| 10:45 – 11:15 | An acetylation-dependent feed-forward reaction enables long-range chromatin interactions Daniel Panne, University of Leicester |
| 11:15 – 11:45 | Coffee and Tea |
| 11:45 – 13:05 | Session 2 – 3D Genome Organization Chair: Hiroshi Kimura |
| 11:45 – 12:15 | Spatial multi-omics for understanding gene expression regulated by cell-cell interaction Yasuyuki Ohkawa, Kyushu University |
| 12:15 – 12:45 | Chromatin behavior in living cells revealed by single-nucleosome imaging/tacking Kazuhiro Maeshima, National Institute of Genetics |
| 12:45 – 13:5 | Visualising chromatin dynamics in living cells at the domain level Andrew Bowman, University of Warwick |
| 13:05 – 13:30 | Lunch |
| 13:30 – 14:30 | Poster session |
| 14:30 – 16:20 | Session 3 – Chromatin in
Development Chair: Shaun Cowley |
| 14:30 – 15:0 | A critical role for H3K9 methylation in mitotic chromosome bookmarking and compaction Mandy Fisher, Imperial College London |
| 15:0 – 15:30 | Quantification of sperm chromatin condensation Yuki Okada, University of Tokyo |
| 15:30 – 16:0 | Canonical PRC1 Is Recruited To Target Genes By JARID2-PRC2 Independently of H3K27me3 Adrian Bracken, Trinity College Dublin |
| 16:0 – 16:20 | JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation Manuel Tavares, UCL Cancer Institute |
| 16:20 – 16:50 | Coffee and Tea |
| 16:50 – 18:00 | Session 4 –
Chromatin and RNA Chair: Jun-ichi Nakayama |
| 16:50 – 17:20 | Understanding and reconstructing small RNA-mediated heterochromatin formation Yuka Iwasaki, Keio University |
| 17:50 – 18:10 | Investigating the effects of LINE1 promoters’ activity in colon cancer Cristina Tufarelli, University of Leicester |
| 19:30 pm | Conference Dinner at College Court |
Tuesday, 23. August 2022
| 9:30 – 09:00 | Coffe and Tea |
| 9:00 – 10:50 | Session 5 – Gene Regulation Chair: Yuki Okada |
|---|---|
| 9:0 – 9:30 | Unlocking the differential activities of HDAC1/2 complexes: How many machines does it take to build a road..? Shaun Cowley, University of Leicester |
| 9:30 – 10:0 | Control of signal-responsive enhancer resetting by chromatin remodelling proteins Brian Hendrich, University of Cambridge |
| 10:0 – 10:30 | Understanding how CpG islands regulate gene expression Rob Klose, University of Oxford |
| 10:30 – 10:50 | Investigating the roles of BET bromodomain proteins in DNA replication and repair Eva Petermann, University of Birmingham |
| 10:50 – 11:20 | Coffee and Tea |
| 11:20 – 13:00 | Session 6 – 3D Genome Organization Chair: Yuka Iwasaki |
| 11:20 – 11:50 | Dynamics of Histone and RNA Polymerase II Modifications in Living Cells Hiroshi Kimura, Tokyo Institute of Technology |
| 11:50 – 12:20 | Replication dynamics identifies the folding principles of the inactive X chromosome Ichiro Hiratani, RIKEN |
| 12:20 – 12:40 | Cohesin-independent STAG proteins interact with RNA and localise to R-loops to promote complex loading Yang Li, University College London, Cancer Institute |
| 12:40 – 13:15 | Lunch |
| 13:15 – 14:00 | Poster session |
| 14:00 – 15:30 | Session 7 – Heterochromatin Chair: Daniel Panne |
| 14:0 – 14:30 | Epigenetic Regulation, Heterochormatin and Antifungal Resistance Robin Allshire, University of Edinburgh |
| 14:30 – 15:0 | Mechanisms regulating Clr4/SUV39H histone methyltransferase activity Junichi Nakayama, National Institute for Basic Biology |
| 15:0 – 15:30 | Histone ubiquitination marks antagonize to compartmentalize the genome Thomas Schalch, University of Leicester |
| 15:30 – 16:00 | Coffee and Tea |
| 16:00 – 17:20 | Session 9 – Chromatin remodelling Chair: John Schwabe |
| 16:0 – 16:20 | Proteomic profiling reveals distinct phases to the restoration of chromatin following DNA replication Constance Alabert, University of Dundee |
| 16:20 – 16:50 | Epigenetic changes arising from acute depletion of the tumour suppressor ARID1A. Tom Owen-Hughes, University of Dundee |
| 16:50 – 17:00 | Closing Remarks and Departure |